Scientists involved in cloning, accuse each other of forgery

Scientists involved in cloning, accuse each other of forgeryThe world of the science of stem cells was plunged into chaos. Former colleagues in the South Korean team, which was once called superstars cloning, a sword in each other's accusations, and scientists are questioning the truth of the greater part of their work - and think about how big will be the damage caused this scandal already controversial area of science. on 16 December The Juice Hwang of Seoul national University announced that it wants to withdraw the report, published in may in the journal Science, which reported a fundamental step in the direction of "therapeutic cloning" is used for the treatment of tissue grown from clones patients ' own cells. This report has been subjected to a barrage of criticism due to inaccuracies in the data, based on which Hwang claimed that created 11 lines of embryonic stem cells, cloned from different people. Then came the question about 5 other reports, including not only the work of Hwang and study his colleagues from the hospital Mizmedi in Seoul. "It's very sad for Korean studies," says Arnold Kriegstein, biologist dealing with stem cells at the University of California, San Francisco. The consequences of this scandal may be even wider, as opponents of the research in the field of cloning and embryonic stem cells will try to make it political capital. Hwang announced the review of the report on the background of the transition in the camp of his enemies Chairman of the Board of the hospital Mizmedi sung Il Ro, previously it supported. Ro repeated assertions sung Chan Kim, a former researcher of the hospital, and now an employee of the University of Pittsburgh, Pennsylvania, who told the Korean media that Hwang had asked him to fabricate the image cell lines, described in the journal Science. At a press conference in Seoul Hwang again stated that the cloned individual stem cell lines, but acknowledged that the data have some problems. He stated that some of the cells died after infection, fungal infection, and suggested that scientists Mizmedi could replace cloned embryonic stem cells from other cells. Now observers don't know what to believe. "Today there are so many conflicting messages," says Doug Melton, a biologist involved in stem cells at Harvard. The list of accusations is growing. Among them distrust the message in 2004 in the journal Science, in which Hwang claimed to have created the first cloned human embryonic stem cells. Leslie Johnson, managing Clinical Testing and Research, laboratory for DNA research in Ridgewood, new Jersey, says that the scheme allegedly the same experiment have different interpretations from the point of view of DNA. As of December 19 Korean scientists said on the Internet that picture in the magazine was assembled on the basis of previously published images. Meanwhile, the journal Nature intends to request DNA testing of the evidence supporting the statement of Hwang about the creation of the first cloned dog, the newspaper writes. Robert Lanza, who heads a rival group on cloning at Advanced Cell Technology in Worcester, Massachusetts, also questioned the work of Hwang on cloning porcine embryos, as reported in the journal Molecular Reproduction and Development. This report withdrawn was not. The story was accompanied by various illustrations showing the level of gene activity, which seem to be identical. Hwang denies that there can be some mistakes. "We'll have to figure it out," says Ralph Gwatkin, chief editor of the magazine. "All the work of Hwang should be subjected to careful scrutiny," says Krigstein. However, it is not limited to: Two reports Mizmedi, the author Hwang is also withdrawn. The author of both - the Prosecutor-hwan Kim. In them are considered non-clone biology of embryonic cells. The first report, published in Biology of Reproduction, was revoked after it was revealed that he illustrated an image, identical to what was published in 2005 in Science in the story about the achievements of Hwang. In the second pictures allegedly different experiments were mirrored copies, the newspaper notes. New Scientist (Russian text

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